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.hd-top-links--links--safety:before{content:"";position:absolute;width:1.875rem;height:1.875rem;left:50%;top:50%;transform:translate(-50%,-50%);background:url(/themes/custom/takeda/images/safety-link.fc37aedd.svg);background-repeat:no-repeat;background-size:contain;background-position:50%;}.hd-header.is-sticky .region-header .hd-header__right .hd-header__menu .hd-top-links.is-sticky .hd-top-links--sub-menu{display:none;}.hd-header.is-sticky .region-header a.user-link{color:#5b7f95;}.hd-header.is-sticky .only-sticky.is-sticky{display:flex;align-items:center;}.hd-header .region-header{color:#5b7f95;}.hd-header .region-header .field--name-field-cta{display:flex;}@media screen and (max-width:1250px){.hd-header .region-header .field--name-field-cta{flex-direction:column;}}.hd-header .region-header .field--name-field-cta a{color:#5b7f95;cursor:pointer;display:flex;align-items:center;font-size:0.875rem;margin-left:0.9375rem;position:relative;text-decoration:underline;white-space:nowrap;}.hd-header .region-header .field--name-field-cta a :hover{color:#5b7f95;}.hd-header .region-header .field--name-field-cta a img{height:1.875rem;width:auto;}.hd-header .region-header .field--name-field-cta a span{padding-left:0.625rem;}@media screen and (max-width:1250px){.hd-header .region-header .field--name-field-cta a span{display:block !important;}}@media (min-width:991px){.hd-header .region-header{padding:1rem 1rem 0 1rem;margin-inline:auto;width:100%;display:flex;justify-content:center;margin:0 auto;}}.hd-header .region-header .hd-header__logo{max-width:6.25rem;padding-right:0;cursor:pointer;}@media screen and (min-width:1250px){.hd-header .region-header .hd-header__logo{max-width:12.5rem;padding-bottom:0.25rem;}}.hd-header .region-header .hd-header__logo img.only-sticky{display:none;max-height:100%;}.hd-header .region-header .hd-header__right{display:flex;flex-direction:column;justify-content:space-between;position:static;}.hd-header .region-header .hd-header__right .hd-header__top{display:none;}@media (min-width:1250px){.hd-header .region-header .hd-header__right .hd-header__top{display:flex;justify-content:flex-end;}}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links{display:flex;align-items:center;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links--user{display:flex;align-items:center;font-size:0.875rem;color:#5b7f95;position:relative;top:0.125rem;margin-right:0.9375rem;flex-shrink:0;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links--user-img{width:1.875rem;height:1.875rem;margin-right:0.4375rem;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links--links{cursor:pointer;font-size:0.875rem;color:#5b7f95;text-decoration:underline;padding:0 1em;border-right:0.0625rem solid rgba(91,127,149,0.5);white-space:nowrap;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links--links--safety{padding-right:0;border-right:none;position:relative;margin-left:0.9375rem;padding-left:2.5rem;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links--links--safety:before{content:"";position:absolute;width:1.875rem;height:1.875rem;left:0;top:50%;transform:translateY(-50%);background:url(/themes/custom/images/safety-link.fc37aedd.svg);background-repeat:no-repeat;background-size:contain;background-position:50%;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links--links--pi{position:relative;margin-left:0.9375rem;padding-left:2.5rem;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links--links--pi:before{content:"";position:absolute;width:1.875rem;height:1.875rem;left:0;top:50%;transform:translateY(-50%);background:url(/themes/custom/images/pi-icon.4d201785.svg);background-repeat:no-repeat;background-size:contain;background-position:50%;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links .field--name-field-cta{display:flex;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links .field--name-field-cta a{color:#5b7f95;cursor:pointer;display:flex;align-items:center;font-size:0.875rem;margin-left:0.9375rem;position:relative;text-decoration:underline;white-space:nowrap;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links .field--name-field-cta a :hover{color:#5b7f95;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links .field--name-field-cta a img{height:1.875rem;width:auto;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links .field--name-field-cta a span{padding-left:0.625rem;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links--sub-menu{background:#f1f4f5;width:100%;opacity:0;pointer-events:none;transition:opacity 0.15s ease;position:absolute;left:0;top:4.5625rem;font-size:0.875rem;font-weight:600;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links--sub-menu.is-active{opacity:1;pointer-events:auto;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links--sub-menu .hd-top-links--links{color:#0f0f0f;font-size:0.875rem;padding-right:0;border-right:none;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links--sub-menu .hd-container{display:flex;justify-content:flex-end;padding-right:7.5rem;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links.is-sticky{padding-left:2em;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links.is-sticky .not-sticky{display:none;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links.is-sticky .hd-top-links--user{margin-right:0;cursor:pointer;flex-shrink:0;padding:1em;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links.is-sticky .hd-top-links--user img{margin-right:0;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links.is-sticky .hd-top-links--user.is-active{background:#f1f4f5;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links.is-sticky .hd-top-links--links--safety p{display:none;}.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links.is-sticky .hd-top-links--links--pi p{display:none;}@media (max-width:991px){.hd-header .region-header .hd-header__right .hd-header__top .hd-top-links.only-sticky{width:100%;display:none;}}.hd-header .region-header .hd-header__right .mobile_toggle{float:right;position:absolute;right:0.9375rem;top:50%;transform:translateY(-50%);width:1.875rem;height:1.875rem;cursor:pointer;background:url(/themes/custom/takeda/images/mobile-menu.689bac50.svg);background-repeat:no-repeat;background-size:contain;background-position:50%;font-size:0;}@media (min-width:1250px){.hd-header .region-header .hd-header__right .mobile_toggle{display:none;}}.hd-header .region-header .hd-header__right .mobile_toggle.open{background:url(/themes/custom/takeda/images/close-interactive-overlay.83c189eb.svg);background-size:2.1875rem;background-repeat:no-repeat;background-position:center;}.hd-header .region-header .hd-header__right .mobile_toggle > img{max-width:2.1875rem;margin-top:0.625rem;cursor:pointer;}.hd-header .region-header .hd-header__right .hd-header__menu{display:none;}@media (min-width:1250px){.hd-header .region-header .hd-header__right .hd-header__menu{display:flex;justify-content:center;}}.hd-header .region-header .hd-header__right .hd-header__menu.mobile_menu{width:100%;float:left;position:absolute;right:0;top:100%;box-shadow:0 1.5625rem 1.125rem rgba(0,0,0,0.3);}@media screen and (max-width:1250px){.hd-header .region-header .hd-header__right .hd-header__menu.mobile_menu{background-color:#ffffff;height:90vh;padding:1rem 1rem 2rem 1rem;display:flex;flex-direction:column;row-gap:4.5rem;}}.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu{display:block;width:100%;justify-content:space-between;align-items:flex-end;padding:0;max-height:60vh;overflow:auto;margin-bottom:0.9375rem;}@media (min-width:1250px){.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu{display:flex;max-height:unset;overflow:unset;margin-bottom:unset;}}.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item{line-height:0.9375rem;text-transform:uppercase;flex:1;padding:1.4em 0.9375rem;font-size:0.75rem;}@media screen and (min-width:1250px){.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item{padding:1rem 1rem 1.5rem 1rem;font-size:0.875rem;}}@media screen and (min-width:1250px){.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item:hover{background:#f1f4f5;}}.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item a{font-size:1.375rem;color:#5b7f95;font-weight:500;letter-spacing:0;line-height:0.9375rem;cursor:pointer;text-transform:uppercase;}@media (min-width:1250px){.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item a{font-size:0.875rem;}}@media screen and (min-width:1250px){.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item .hd-menu__sub-menu{background:#f1f4f5;width:100%;opacity:0;pointer-events:none;transition:opacity 0.15s ease;position:absolute;left:0;margin-top:1.2em;text-transform:uppercase;font-size:0.75rem;font-weight:600;padding:1.5em 1em;max-width:revert;}}@media (min-width:1250px){.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item .hd-menu__sub-menu{margin-top:1.7em;}}.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item .hd-menu__sub-menu.hd-container{display:none;margin-top:0.625rem;padding:0.6rem 0;}.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item .hd-menu__sub-menu.hd-container.is-visible{display:flex;flex-direction:column;opacity:1 !important;}.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item .hd-menu__sub-menu.hd-container.is-visible a{font-size:0.9375rem;line-height:1.125rem;font-weight:500;padding:0.625rem 0;display:inline-block;}@media screen and (min-width:1250px){.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item .hd-menu__sub-menu.hd-container{padding:1rem 0;width:100%;display:flex;justify-content:center;margin-top:1.5rem;}}.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item .hd-menu__sub-menu .hd_mbnav{flex:1;}@media (min-width:1250px){.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item .hd-menu__sub-menu .hd_mbnav .hd-menu__item:hover{background:#f1f4f5;}}.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item .hd-menu__sub-menu .hd_mbnav .hd-menu__item a{font-size:0.875rem;color:black;font-weight:500;letter-spacing:0;line-height:0.9375rem;cursor:pointer;text-transform:uppercase;}@media (min-width:1250px){.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item .hd-menu__sub-menu .hd_mbnav .hd-menu__item.is-active{margin-left:-0.625rem;}}.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item .hd-menu__sub-menu > div{width:100%;text-align:left;max-width:100%;}@media screen and (min-width:1250px){.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item .hd-menu__sub-menu > div{text-align:center;flex:1;max-width:12.5rem;}}.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item:hover .hd-menu__sub-menu{opacity:1;pointer-events:auto;justify-content:center;}@media (min-width:1250px){.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item.is-active{padding-left:1.8125rem;}}.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item.is-active a{color:#0f0f0f;transition:all 0.2s ease;}.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item.is-active:before{transition:all 0.2s ease;content:"";display:block;width:0.3125rem;height:1.125rem;background:#ae2573;position:relative;top:1rem;margin-left:-0.625rem;margin-top:-0.1875rem;}.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item sup{position:absolute;font-size:0.5rem;margin-top:-0.125rem;}.hd-header .region-header .hd-header__right .hd-header__menu .hd-menu__item.is-disabled{pointer-events:none;}.hd-header .region-header .hd-header__right .hd-header__menu .hd-top-links.only-sticky.is-sticky{display:none;}.hd-header .region-header .hd-header__right .hd-header__menu .hd-header-mobile__nav--secondary{left:0;bottom:3.5rem;}@media (min-width:1250px){.hd-header .region-header .hd-header__right .hd-header__menu .hd-header-mobile__nav--secondary{display:none;bottom:1.25rem;}}.hd-header .region-header .hd-header__right .hd-header__menu .hd-header-mobile__nav--secondary--top-row{display:flex;align-items:center;border-bottom:0.0625rem solid rgba(91,127,149,0.4);padding-bottom:1em;}.hd-header .region-header .hd-header__right .hd-header__menu .hd-header-mobile__nav--secondary--bottom-row{display:flex;padding-top:1em;flex-direction:column;gap:0.625rem;}@media screen and (min-width:768px){.hd-header .region-header .hd-header__right .hd-header__menu .hd-header-mobile__nav--secondary--bottom-row{flex-direction:row;}}.hd-header .region-header .hd-header__right .hd-header__menu .hd-header-mobile__nav--secondary .hd-top-links.only-sticky{display:none !important;}.hd-header .region-header .hd-header__right .hd-header__menu .hd-header-mobile__nav--secondary .hd-top-links--user{display:flex;align-items:center;font-size:1.1em;margin-right:2em;}.hd-header .region-header .hd-header__right .hd-header__menu .hd-header-mobile__nav--secondary .hd-top-links--user img{margin-right:0.625rem;width:2.5rem;}.hd-header .region-header .hd-header__right .hd-header__menu .hd-header-mobile__nav--secondary .hd-top-links--user-name{font-size:1em;font-weight:600;}.hd-header .region-header .hd-header__right .hd-header__menu .hd-header-mobile__nav--secondary .hd-top-links--sign-out{font-size:0.875rem;text-decoration:underline;}.hd-header .region-header .hd-header__right .hd-header__menu .hd-header-mobile__nav--secondary .hd-top-links--links{font-size:0.875rem;text-decoration:underline;margin-right:2em;}.hd-header .region-header .hd-header__right .hd-header__menu .hd-header-mobile__nav--secondary .hd-top-links--links--safety{position:relative;padding-left:2rem;}.hd-header .region-header .hd-header__right .hd-header__menu .hd-header-mobile__nav--secondary .hd-top-links--links--safety p{color:#5b7f95;}.hd-header .region-header .hd-header__right .hd-header__menu .hd-header-mobile__nav--secondary .hd-top-links--links--safety:before{content:"";position:absolute;width:1.5625rem;height:1.5625rem;left:0;top:50%;transform:translateY(-50%);background:url(/themes/custom/takeda/images/safety-link.fc37aedd.svg);background-repeat:no-repeat;background-size:contain;background-position:50%;}.hd-header .region-header .hd-header__right .hd-header__menu .hd-header-mobile__nav--secondary .hd-top-links--links--pi{position:relative;padding-left:2rem;}.hd-header .region-header .hd-header__right .hd-header__menu .hd-header-mobile__nav--secondary .hd-top-links--links--pi p{color:#5b7f95;}.hd-header .region-header .hd-header__right .hd-header__menu .hd-header-mobile__nav--secondary .hd-top-links--links--pi:before{content:"";position:absolute;width:1.5625rem;height:1.5625rem;left:0;top:50%;transform:translateY(-50%);background:url(/themes/custom/takeda/images/pi-icon.4d201785.svg);background-repeat:no-repeat;background-size:contain;background-position:50%;}@media screen and (max-width:1250px){.hd-header .field__item:not(:last-child) a{margin-bottom:1rem;}}@media screen and (min-width:1250px){.hd-header .field__item:not(:last-child) a span{padding-right:0.625rem;border-right:0.0625rem solid rgba(91,127,149,0.5);}}.hd-header .hd-container{width:100%;display:flex;justify-content:center;padding-top:0.5rem;padding-bottom:0.5rem;}@media screen and (min-width:1250px){.hd-header .hd-container{margin-inline:auto;padding:1.625rem 1rem 0 1rem;}}.hd-header .hd-container > div{flex:1;}@media screen and (min-width:1250px){.hd-header .hd-container:not(.hd-menu__sub-menu){padding:1em 1em 0 1em;}}.before-header .field--name-field-cta{background-color:#363739;}@media screen and (min-width:1250px){.before-header .field--name-field-cta{display:none;}}.before-header .field--name-field-cta .field__items{max-width:1450px;margin:0 auto;}.before-header .field--name-field-cta .field__item:first-child a{border-top:1px solid white;}.before-header .field--name-field-cta .field__item a{padding:1em;border-bottom:1px solid white;color:white;display:block;font-size:14px;}.before-header .field--name-field-cta .field__item img{display:none;}.hd-footer{font-family:Heebo-Regular,Heebo,sans-serif;background:#f1f4f5;color:#5b7f95;padding:2rem 0 1.5rem 0;font-size:0.875rem;position:relative;}@media screen and (min-width:768px){.hd-footer{padding:2rem 9.0625rem 3rem;}}.hd-footer .hd-app-container{display:flex;align-items:center;flex-direction:column;text-align:center;}.hd-footer .hd-app-container.footer_menu{margin-top:3.75rem;}@media screen and (min-width:768px){.hd-footer .hd-app-container.text_content .hd-footer__copyright{max-width:29.1875rem;line-height:1.125rem;}}.hd-footer .hd-app-container.text_content .field--name-field-right-side-text p{color:#5b7f95;}@media screen and (min-width:768px){.hd-footer .hd-app-container{flex-direction:row;justify-content:space-between;text-align:left;}.hd-footer .hd-app-container.footer_menu{justify-content:center;}.hd-footer .hd-app-container.text_content{justify-content:center;text-align:center;}}@media screen and (min-width:991px){.hd-footer .hd-app-container.text_content{justify-content:space-between;text-align:left;}.hd-footer .hd-app-container.text_content .field--name-field-right-side-text p{line-height:1.25rem;font-size:0.875rem;}}@media screen and (min-width:1100px){.hd-footer .hd-app-container.footer_menu{margin-top:0;justify-content:flex-end;}}.hd-footer__menu{display:flex;justify-content:center;flex-direction:column;gap:1.875rem;}@media screen and (min-width:768px){.hd-footer__menu{flex-direction:row;align-items:center;gap:unset;}}.hd-footer__menu--item p{font-family:"Heebo",sans-serif;font-size:0.875rem;font-weight:500;text-decoration:underline;color:#0f0f0f;border-right:none;padding:0;cursor:pointer;line-height:1.25rem;margin-top:-3px;}.hd-footer__menu--item:hover{color:#0f0f0f;}@media screen and (max-width:768px){.hd-footer__menu--item:last-child{margin-bottom:0;}}@media screen and (min-width:768px){.hd-footer__menu--item{padding:0 1.375rem;margin-bottom:0;border-right:0.0625rem solid #0f0f0f;height:12px;}.hd-footer__menu--item:last-child{border-right:none;padding-right:0;}}.hd-footer__logo{position:absolute;top:0;max-width:8.75rem;margin:0 auto;}@media screen and (min-width:768px){.hd-footer__logo{left:50%;transform:translate(-50%);max-width:7.5rem;margin:unset;}}@media screen and (min-width:1100px){.hd-footer__logo{top:0.875rem;left:0.875rem;transform:translate(0);}}.hd-footer__copyright p,.hd-footer__job-code p{color:#5b7f95;font-size:0.875rem;line-height:1.25rem;}.hd-footer__job-code{margin-top:1.875rem;}@media screen and (min-width:768px){.hd-footer__job-code{margin-top:0;}}.hd-footer .error-page .footer{font-size:1.625rem;color:#595454;padding-top:0.5rem;}.hd-footer .error-page .footer a{text-decoration:underline;}.region-footer{position:relative;width:100%;max-width:1360px;margin-left:auto;margin-right:auto;}.region-footer .contextual-region{position:static;margin:0;padding:0;}.main-container{width:100%;max-width:1360px;margin:0 auto;}.region.region-content{padding-left:1rem;padding-right:1rem;}@media screen and (min-width:768px){.region.region-content{padding-left:0;padding-right:0;}}.hd-grid .hd-cell{padding-top:5.625rem;}.hd-grid .hd-cell .hd-cell__image{position:absolute;content:"";display:block;width:9.375rem;height:9.375rem;margin:0 auto 2em;top:-4.375rem;z-index:1;}.hd-grid .hd-cell .hd-cell__image > div{width:100%;height:100%;}.hd-grid .hd-cell .hd-cell__image > div img{width:100%;height:100%;object-fit:contain;}.splide__arrow{width:2.5rem;height:2.5rem;}.splide__arrow svg{width:100%;height:100%;}.primary .splide__arrow svg{fill:#3eb1c8;}.secondary .splide__arrow svg{fill:#d9027d;}.primary-dark .splide__arrow svg{fill:#5b7f95;}.hd-protection .hd-carousel__controls{width:100%;display:flex;}.hd-protection .hd-carousel__slide_2,.hd-protection .hd-carousel__slide_3{display:none;}.hd-protection .hd-carousel__viewport{max-width:62.5rem;position:relative;margin:auto;}.hd-protection .prev,.hd-protection .next{cursor:pointer;position:absolute;top:50%;width:auto;padding:1rem;margin-top:-1.375rem;color:white;font-weight:bold;font-size:1.125rem;transition:0.6s ease;border-radius:0 0.1875rem 0.1875rem 0;user-select:none;}.hd-protection .next{right:0;border-radius:0.1875rem 0 0 0.1875rem;}.hd-protection .title-cell{padding-left:0;width:33%;}.hd-protection .hd-cell.cell-2.title-cell{width:66%;padding:0;}@media only screen and (min-width:835px){.lg{display:block;}.sm{display:none;}}@media only screen and (max-width:835px){.hd-grid .hd-cell.cell-2.title-cell{display:block;flex:unset;margin:auto;width:100%;}.sm{display:block;}.sm .field--type-text-long{width:80%;margin-left:auto;margin-right:auto;text-align:center;}.lg{display:none;}.hd-protection .hd-protection__content .hd-cell{margin:2.5rem 0 0 0;position:relative;display:flex;padding-top:5.625rem;width:auto;flex-basis:auto;}.hd-protection .hd-protection__content .hd-cell:after{border:none !important;}.hd-protection .hd-protection__content .hd-cell:before{left:calc(50% - 4.6875rem) !important;}.carousel-2 .hd-carousel__controls a{border-bottom:none;color:#5b7f95;font-size:2rem;font-weight:200;}.carousel-3 .hd-carousel__controls a{border-bottom:none;color:#d9027d;font-size:2rem;font-weight:200;}.hd-protection .title-cell.hide-lg{margin-top:2.5rem;width:100%;}}.hcp.section img{display:inline-block;}.main-content.hcp-main-content{float:none;margin-inline:auto;}@media screen and (max-width:991px){.administering-mobile-layout .field--name-field-article-section .field__item:nth-child(3) .paragraph{display:flex;align-items:center;justify-content:center;}.administering-mobile-layout .field--name-field-article-section .field__item:nth-child(3) .paragraph .left-component{order:2;}.administering-mobile-layout .field--name-field-article-section .field__item:nth-child(3) .paragraph .field--name-field-sbs-right-component{order:1;}.administering-mobile-layout .field--name-field-article-section .field__item:nth-child(10){border:1px solid #DBE2E9;border-radius:20px;padding-top:1em;}}.hexagon{position:absolute;width:3.75rem;height:2.165rem;background-color:#DBE2E9;margin:1.0825rem 0;right:0;transform:rotate(-60deg);top:-1.5625rem;border:none;}.hexagon .hd-chevron{background-image:url(/themes/custom/takeda/src/images/right-chevron.svg);background-repeat:no-repeat;background-position:center;width:100%;height:100%;margin:0.625rem;top:-0.5rem;position:absolute;right:-0.625rem;z-index:1;transform:rotate(-30deg);}.hexagon:before{bottom:100%;border-bottom:1.0825rem solid #DBE2E9;right:0;}.hexagon:after{top:100%;width:0;border-top:1.0825rem solid #DBE2E9;right:0;}@media screen and (min-width:768px){.hexagon{display:none;}}.hexagon:before,.hexagon:after{content:"";position:absolute;width:0;border-left:1.875rem solid transparent;border-right:1.875rem solid transparent;}.clinical-program-page .hd-app-container{flex-direction:column;}@media screen and (min-width:991px){.clinical-program-page .hd-app-container{flex-direction:row;}}.main-content-container{width:90%;max-width:85rem;margin-left:auto;margin-right:auto;}@media screen and (min-width:768px){.main-content-container{width:93%;}}.main-content-container.has-sidebar{display:flex;flex-direction:column;}@media screen and (min-width:991px){.main-content-container.has-sidebar{flex-direction:row;}}.main-content-container.has-sidebar .main-content{flex:1;margin:0;}@media screen and (min-width:835px){.main-content-container.has-sidebar .main-content{width:100%;}}@media screen and (min-width:991px){.main-content-container.has-sidebar .main-content{margin-left:3.75rem;max-width:68.125rem;width:70%;}}.main-content-container.has-sidebar .main-content .card-group{flex-direction:column;}.main-content-container.has-sidebar .main-content .card-group__item{margin-right:0;margin-left:0;}.main-content-container.has-sidebar .main-content .card-group__item:first-child{margin-bottom:3rem;}@media screen and (min-width:75rem){.main-content-container.has-sidebar .main-content .card-group{flex-direction:row;}.main-content-container.has-sidebar .main-content .card-group__item:first-child{margin-right:3.75rem;}}.main-content-container #Serostatus .interactive-area__content{max-width:unset;top:52%;padding-bottom:48px;}.main-content-container #Serostatus .interactive-area__content .interactive-area__content--details div{width:100%;}.main-content-container #Serostatus .interactive-area__content .interactive-area__content--details div img{max-width:unset;}.layout-no-sidebars .main-content{margin-top:50px;}@media screen and (max-width:991px){.impacts-of-dengue .hd-app-container{flex-direction:column;}.impacts-of-dengue .hd-app-container .hd-page-body:not(.patients-body){width:100%;padding-left:0;}}.impacts-of-dengue .hd-app-container .hd-page-body.patients-body{margin-left:auto;}.education-events .main-content-container{max-width:21.4375rem;width:90%;margin-bottom:2.125rem;}@media screen and (min-width:768px){.education-events .main-content-container{width:90%;max-width:unset;}}@media screen and (min-width:991px){.education-events .main-content-container{margin-bottom:12.1875rem;max-width:56.375rem;}}.education-events .event__content-info .field--name-field-location.field--type-address{display:flex;}.education-events .event__content-info .field--name-field-location.field--type-address .address{margin-top:0;}.address:last-child br{display:none;}.mode-of-action .main-content-container{max-width:67.625rem;}.mode-of-action .text-paragraph.container{max-width:100%;}.public-page h2,.public-page p{color:#363739;}.public-page .region-header{justify-content:flex-start;}.public-page ul li:before{background-color:#00CCFF;}.public-page #block-inpagemenublock .in-page-navigation .hd-page-navigation__item a{color:#363739;}.public-page a{color:#00CCFF;}.public-page #block-pagetitle .page-title{border-color:#00CCFF;color:#363739;}.public-page #block-inpagemenublock .in-page-navigation .hd-page-navigation__item.is-active::before{background-color:#00CCFF;}.block-views-blockresource-videos-block-1{grid-area:3 / 1 / 3 / 3;}.resource-videos-section{display:flex;flex-direction:column;width:100%;margin:50px 0;}.video-block-container{display:grid;flex-direction:row;grid-template-columns:1fr 1fr 1fr 1fr;gap:20px;}@media only screen and (min-width:320px){.video-block-container{flex-direction:column;grid-template-columns:1fr;}}@media only screen and (min-width:820px){.video-block-container{flex-direction:row;grid-template-columns:1fr 1fr;}}@media only screen and (min-width:1025px){.video-block-container{grid-template-columns:1fr 1fr 1fr 1fr;}}h2.resource-section-title{color:#5b7f95;font-weight:500;font-size:1.75rem;line-height:2rem;margin-bottom:0.75rem;}.video-teaser-block{width:100%;height:150px;background-repeat:no-repeat;background-position:center;background-size:cover;display:block;position:relative;overflow:hidden;border-radius:4px;}@media only screen and (max-width:835px){.video-teaser-block{width:100%;}}.video-teaser-block::before{position:absolute;top:0px;left:0px;z-index:1;width:100%;height:100%;background-image:linear-gradient(rgba(0,0,0,0.7),rgba(0,0,0,0.7));content:"";overflow:hidden;}.video-teaser-block h3{position:absolute;top:50%;transform:translateY(-50%);left:10px;color:#fff;z-index:2;font-size:18px;max-width:90%;}.play-tab{display:flex;z-index:2;position:absolute;top:4px;right:4px;background:#d9027d;padding:4px 8px;border-radius:8px;}.play-tab span{color:#fff;font-size:14px;}.play-tab img{width:12px;margin-left:8px;}.resource-video-page{margin-top:50px;}.resource-video-page__video{max-width:1000px;margin:0 auto;}.resource-video-page__body{max-width:1000px;margin:50px 0;}.resource-video-page__jobcode{display:flex;justify-content:center;gap:10px;margin:50px 0;color:black;font-size:1.125rem;}
@font-face{font-family:'Heebo';src:url(/themes/custom/takeda/fonts/heebo/Heebo-Black.eot);src:url(/themes/custom/takeda/fonts/heebo/Heebo-Black.eot#iefix) format('embedded-opentype'),url(/themes/custom/takeda/fonts/heebo/Heebo-Black.woff2) format('woff2'),url(/themes/custom/takeda/fonts/heebo/Heebo-Black.woff) format('woff'),url(/themes/custom/takeda/fonts/heebo/Heebo-Black.ttf) format('truetype'),url(/themes/custom/takeda/fonts/heebo/Heebo-Black.svg#Heebo-Black) format('svg');font-weight:900;font-style:normal;font-display:swap;}@font-face{font-family:'Heebo';src:url(/themes/custom/takeda/fonts/heebo/Heebo-Bold.eot);src:url(/themes/custom/takeda/fonts/heebo/Heebo-Bold.eot#iefix) format('embedded-opentype'),url(/themes/custom/takeda/fonts/heebo/Heebo-Bold.woff2) format('woff2'),url(/themes/custom/takeda/fonts/heebo/Heebo-Bold.woff) format('woff'),url(/themes/custom/takeda/fonts/heebo/Heebo-Bold.ttf) format('truetype'),url(/themes/custom/takeda/fonts/heebo/Heebo-Bold.svg#Heebo-Bold) format('svg');font-weight:bold;font-style:normal;font-display:swap;}@font-face{font-family:'Heebo';src:url(/themes/custom/takeda/fonts/heebo/Heebo-Thin.eot);src:url(/themes/custom/takeda/fonts/heebo/Heebo-Thin.eot#iefix) format('embedded-opentype'),url(/themes/custom/takeda/fonts/heebo/Heebo-Thin.woff2) format('woff2'),url(/themes/custom/takeda/fonts/heebo/Heebo-Thin.woff) format('woff'),url(/themes/custom/takeda/fonts/heebo/Heebo-Thin.ttf) format('truetype'),url(/themes/custom/takeda/fonts/heebo/Heebo-Thin.svg#Heebo-Thin) format('svg');font-weight:100;font-style:normal;font-display:swap;}@font-face{font-family:'Heebo';src:url(/themes/custom/takeda/fonts/heebo/Heebo-ExtraLight.eot);src:url(/themes/custom/takeda/fonts/heebo/Heebo-ExtraLight.eot#iefix) format('embedded-opentype'),url(/themes/custom/takeda/fonts/heebo/Heebo-ExtraLight.woff2) format('woff2'),url(/themes/custom/takeda/fonts/heebo/Heebo-ExtraLight.woff) format('woff'),url(/themes/custom/takeda/fonts/heebo/Heebo-ExtraLight.ttf) format('truetype'),url(/themes/custom/takeda/fonts/heebo/Heebo-ExtraLight.svg#Heebo-ExtraLight) format('svg');font-weight:200;font-style:normal;font-display:swap;}@font-face{font-family:'Heebo';src:url(/themes/custom/takeda/fonts/heebo/Heebo-Light.eot);src:url(/themes/custom/takeda/fonts/heebo/Heebo-Light.eot#iefix) format('embedded-opentype'),url(/themes/custom/takeda/fonts/heebo/Heebo-Light.woff2) format('woff2'),url(/themes/custom/takeda/fonts/heebo/Heebo-Light.woff) format('woff'),url(/themes/custom/takeda/fonts/heebo/Heebo-Light.ttf) format('truetype'),url(/themes/custom/takeda/fonts/heebo/Heebo-Light.svg#Heebo-Light) format('svg');font-weight:300;font-style:normal;font-display:swap;}@font-face{font-family:'Heebo';src:url(/themes/custom/takeda/fonts/heebo/Heebo-SemiBold.eot);src:url(/themes/custom/takeda/fonts/heebo/Heebo-SemiBold.eot#iefix) format('embedded-opentype'),url(/themes/custom/takeda/fonts/heebo/Heebo-SemiBold.woff2) format('woff2'),url(/themes/custom/takeda/fonts/heebo/Heebo-SemiBold.woff) format('woff'),url(/themes/custom/takeda/fonts/heebo/Heebo-SemiBold.ttf) format('truetype'),url(/themes/custom/takeda/fonts/heebo/Heebo-SemiBold.svg#Heebo-SemiBold) format('svg');font-weight:600;font-style:normal;font-display:swap;}@font-face{font-family:'Heebo';src:url(/themes/custom/takeda/fonts/heebo/Heebo-Regular.eot);src:url(/themes/custom/takeda/fonts/heebo/Heebo-Regular.eot#iefix) format('embedded-opentype'),url(/themes/custom/takeda/fonts/heebo/Heebo-Regular.woff2) format('woff2'),url(/themes/custom/takeda/fonts/heebo/Heebo-Regular.woff) format('woff'),url(/themes/custom/takeda/fonts/heebo/Heebo-Regular.ttf) format('truetype'),url(/themes/custom/takeda/fonts/heebo/Heebo-Regular.svg#Heebo-Regular) format('svg');font-weight:normal;font-style:normal;font-display:swap;}@font-face{font-family:'Heebo';src:url(/themes/custom/takeda/fonts/heebo/Heebo-ExtraBold.eot);src:url(/themes/custom/takeda/fonts/heebo/Heebo-ExtraBold.eot#iefix) format('embedded-opentype'),url(/themes/custom/takeda/fonts/heebo/Heebo-ExtraBold.woff2) format('woff2'),url(/themes/custom/takeda/fonts/heebo/Heebo-ExtraBold.woff) format('woff'),url(/themes/custom/takeda/fonts/heebo/Heebo-ExtraBold.ttf) format('truetype'),url(/themes/custom/takeda/fonts/heebo/Heebo-ExtraBold.svg#Heebo-ExtraBold) format('svg');font-weight:bold;font-style:normal;font-display:swap;}@font-face{font-family:'Heebo';src:url(/themes/custom/takeda/fonts/heebo/Heebo-Medium.eot);src:url(/themes/custom/takeda/fonts/heebo/Heebo-Medium.eot#iefix) format('embedded-opentype'),url(/themes/custom/takeda/fonts/heebo/Heebo-Medium.woff2) format('woff2'),url(/themes/custom/takeda/fonts/heebo/Heebo-Medium.woff) format('woff'),url(/themes/custom/takeda/fonts/heebo/Heebo-Medium.ttf) format('truetype'),url(/themes/custom/takeda/fonts/heebo/Heebo-Medium.svg#Heebo-Medium) format('svg');font-weight:500;font-style:normal;font-display:swap;}
.administering-qdenga #node-69{max-width:60.8125rem;margin:0 auto;}.administering-qdenga #node-69 .side-by-side{max-width:70.5rem;}@media screen and (max-width:991px){.administering-qdenga .side-by-side > div .center.paragraph--type--card{margin:3rem 0 1rem 0;}}@media screen and (max-width:991px){.administering-qdenga .side-by-side > div:first-child{margin:0 auto 0 auto;}}@media screen and (max-width:768px){.administering-qdenga .side-by-side .download-file.center{max-width:unset;}}.administering-qdenga .media .field--type-image .field__item img{height:auto;width:100%;max-width:43.75rem;}@media screen and (min-width:991px){.administering-qdenga .media .field--type-image .field__item img{height:auto;width:100%;max-width:100%;}}
.paragraph--type--focus-box{width:100%;box-sizing:border-box;background:white;border:2px solid #5b7f95;font-weight:500;text-align:left;padding:0.7em 2.7em;scroll-margin-block-start:8em;max-width:65.625rem;margin:0 auto;}.paragraph--type--focus-box p{margin-block-start:1em;margin-block-end:1em;}.paragraph--type--focus-box.primary{border:4px solid #00CCFF;border-radius:18px;}
.text-paragraph{margin-bottom:1rem;}.text-paragraph.container{max-width:100%;width:100%;margin-inline:auto;margin:0;}@media screen and (min-width:768px){.text-paragraph.container{max-width:78.75rem;}}@media screen and (min-width:768px){.text-paragraph{margin-bottom:0;}}.text-paragraph h1{color:#5b7f95;font-weight:700;font-size:1.5rem;padding-bottom:0.625rem;margin-bottom:1.875rem;}.text-paragraph h1 sup{line-height:1;top:-1.5em;}.text-paragraph h1.aqua{color:#3eb1c8;}.text-paragraph h1.storm{color:#5b7f95;}.text-paragraph h2{color:#5b7f95;font-weight:500;font-size:1.75rem;line-height:2rem;margin-bottom:2rem;}@media screen and (min-width:991px){.text-paragraph h2{margin-bottom:0.75rem;}}.text-paragraph h2.section-title{font-size:2rem;}.text-paragraph h2.aqua{color:#3eb1c8;}.text-paragraph h3{color:#5b7f95;font-weight:500;line-height:2rem;font-size:1.375rem;margin-bottom:0.5rem;margin-top:0.75rem;}@media screen and (min-width:991px){.text-paragraph h3{margin-bottom:0.75rem;margin-top:0;}}.text-paragraph h3.magenta{color:#d9027d;padding-bottom:1rem;}.text-paragraph h3.aqua{color:#3eb1c8;}.text-paragraph h4{color:#5b7f95;font-weight:400;line-height:1.3;font-size:1.125rem;}.text-paragraph h4.magenta{color:#d9027d;padding-bottom:1rem;}.text-paragraph p,.text-paragraph li{color:black;position:relative;line-height:1.75rem;font-size:1.125rem;}.text-paragraph ul{margin-top:1.25rem;padding-left:0;}.text-paragraph ul > li ul{padding-left:0;margin-top:1rem;}.text-paragraph ul > li ul li{font-size:1rem;font-weight:300;font-family:HeeboLight,Heebo,sans-serif;}.text-paragraph p{padding-left:0;margin:0.875rem 0;}@media screen and (min-width:991px){.text-paragraph p{margin:2rem 0;}}.text-paragraph .paragraph-link{margin:0.625rem 0;}.text-paragraph .paragraph-link a{color:black;border-bottom:0.0625rem solid #595454;}.text-paragraph .paragraph-link:hover a{color:#3eb1c8;border-bottom-color:#3eb1c8;}.path-frontpage .text-paragraph{margin-bottom:1rem;}@media screen and (min-width:768px){.path-frontpage .text-paragraph.container{max-width:62.75rem;}}
#block-pagetitle{width:100%;}#block-pagetitle .page-title{color:#3eb1c8;font-size:calc(2rem - 2px);margin-bottom:3.125rem;max-width:fit-content;font-family:HeeboBold,Heebo,sans-serif;font-weight:700;padding-bottom:1.5rem;border-bottom:4px solid #d9027d;}@media screen and (min-width:768px){#block-pagetitle .page-title{font-size:2.5rem;margin-bottom:3.125rem;}}#block-pagetitle .page-title-hidden h1.page-title{display:none;}.page-title-hidden #block-pagetitle{display:none;}
#block-inpagemenublock{padding:0;border:none;background:transparent;}#block-inpagemenublock .in-page-navigation{margin-top:-1.25rem;background:#ffffff;margin-bottom:1.875rem;position:relative;z-index:1;}@media screen and (min-width:991px){#block-inpagemenublock .in-page-navigation{flex-basis:14.125rem;width:14.125rem;}}#block-inpagemenublock .in-page-navigation .hd-page-navigation{margin-bottom:5em;background:#ffffff;display:none;}#block-inpagemenublock .in-page-navigation .hd-page-navigation__item{border:0.0625rem solid #DBE2E9;cursor:pointer;position:relative;padding:0.9375rem;text-align:left;}#block-inpagemenublock .in-page-navigation .hd-page-navigation__item a{color:#5b7f95;border:none;}#block-inpagemenublock .in-page-navigation .hd-page-navigation__item a:hover{background:#f1f4f5;}#block-inpagemenublock .in-page-navigation .hd-page-navigation__item.is-active{font-weight:bold;}#block-inpagemenublock .in-page-navigation .hd-page-navigation__item.is-active::before{content:"";display:block;width:0.3125rem;height:100%;position:absolute;top:0;left:0;background:#d9027d;}@media screen and (min-width:991px){#block-inpagemenublock .in-page-navigation .hd-page-navigation{display:block;width:100%;max-width:15.625rem;margin:0 0 1rem 0;position:absolute;top:3%;background:#ffffff;box-shadow:0.0625rem 0.0625rem 0.375rem rgba(15,15,15,0.1);border-top:0.125rem solid rgba(91,127,149,0.1);border-bottom:0.125rem solid rgba(91,127,149,0.5);}#block-inpagemenublock .in-page-navigation .hd-page-navigation__item.is-active{display:block;width:100%;}}#block-inpagemenublock .in-page-navigation.is-sticky{position:fixed;top:21.2rem;width:90%;z-index:888;}@media screen and (min-width:768px){#block-inpagemenublock .in-page-navigation.is-sticky{width:93%;}}@media screen and (min-width:991px){#block-inpagemenublock .in-page-navigation.is-sticky{width:13.125rem;max-width:13.125rem;padding-top:5rem;margin-bottom:9.375rem;position:sticky;}#block-inpagemenublock .in-page-navigation.is-sticky.bottom{top:3.125rem;}}@media screen and (min-width:1020px){#block-inpagemenublock .in-page-navigation.is-sticky{width:13.125rem;max-width:13.125rem;padding-top:12.25rem;}}#block-inpagemenublock .in-page-navigation .hd-page-navigation--mobile__label{padding:0.9375rem;border-bottom:0.125rem solid rgba(91,127,149,0.5);box-shadow:0.0625rem 0.0625rem 0.375rem rgba(15,15,15,0.1);position:relative;font-weight:600;display:flex;align-items:center;justify-content:space-between;transition:all 0.5s ease;}#block-inpagemenublock .in-page-navigation .hd-page-navigation--mobile__label a{color:#3b3b3b !important;}#block-inpagemenublock .in-page-navigation .hd-page-navigation--mobile__label::after{content:"";display:block;width:1.25rem;height:1.25rem;background:url(/themes/custom/takeda/images/chevron-secondary-color.af2eaf14.svg);background-repeat:no-repeat;background-size:contain;background-position:50%;transition:all 0.5s ease;}#block-inpagemenublock .in-page-navigation .hd-page-navigation--mobile__label.is-active{border-bottom:0.125rem solid transparent;}#block-inpagemenublock .in-page-navigation .hd-page-navigation--mobile__label.is-active::after{transform:rotate(180deg);transition:all 0.5s ease;}@media screen and (max-width:991px){#block-inpagemenublock .in-page-navigation .hd-page-navigation--mobile__label.is-active ~ .hd-page-navigation{display:block;}}@media screen and (min-width:991px){#block-inpagemenublock .in-page-navigation .hd-page-navigation--mobile__label{display:none;}}#block-inpagemenublock .in-page-navigation .hd-page-navigation--mobile__label.original-label{color:#5b7f95;font-family:Heebo,serif;font-size:1.125rem;letter-spacing:0;line-height:1.6875rem;}.hd-page-navigation__item.is-active .hd-menu__sub-menu .hd-page-navigation__item.is-active:before{content:"";display:none;width:0;height:0;position:absolute;top:0;left:0;background:none;}.hd-page-navigation--mobile__label + .hd-page-navigation,.hd-page-navigation--mobile__label + div{visibility:hidden;opacity:0;transition:all 0.5s ease;display:none;}@media screen and (min-width:991px){.hd-page-navigation--mobile__label + .hd-page-navigation,.hd-page-navigation--mobile__label + div{visibility:visible;opacity:1;display:block;transition:all 0.5s ease;}}.hd-page-navigation--mobile__label.is-active + .hd-page-navigation,.hd-page-navigation--mobile__label.is-active + div{visibility:visible;opacity:1;transition:all 0.5s ease;display:block;}@media screen and (min-width:991px){.hd-page-navigation--mobile__label + .layout-tablet-upper--block{visibility:visible;opacity:1;}.hd-page-navigation--mobile__label + .hd-page-navigation{visibility:visible;opacity:1;}}.sidebar,#sidebar-first{position:relative;margin:-63px 0 0 0;}.sidebar .section,#sidebar-first .section{padding-inline:0;}@media screen and (min-width:991px){.sidebar,#sidebar-first{flex-basis:210px;max-width:210px;left:0;height:100%;top:0;position:sticky;margin:0;}}
.hd-page__banner{margin-bottom:3rem;}.hd-page__banner img{height:auto;max-width:100%;margin:auto;}.hd-page__banner .field--type-image{width:100%;}.hd-page__banner .field--type-image img{object-fit:cover;width:100%;margin:0;}
#block-adverseeventsreporting,#block-adverseeventsreportingblock2{border-top:1px solid #5b7f95;border-bottom:1px solid #5b7f95;text-align:center;padding:0.5em 0;}#block-adverseeventsreporting a,#block-adverseeventsreportingblock2 a{position:relative;display:inline-block;box-sizing:border-box;padding:0 3em;}@media screen and (min-width:991px){#block-adverseeventsreporting a,#block-adverseeventsreportingblock2 a{padding:0;}}#block-adverseeventsreporting a::before,#block-adverseeventsreportingblock2 a::before{content:" ";position:absolute;top:1.5em;right:1.2em;height:1.4em;width:1.4em;border-radius:50%;background:white;box-sizing:border-box;border:2px solid black;}@media screen and (min-width:727px){#block-adverseeventsreporting a::before,#block-adverseeventsreportingblock2 a::before{top:0;right:1em;}}@media screen and (min-width:991px){#block-adverseeventsreporting a::before,#block-adverseeventsreportingblock2 a::before{right:-2em;}}#block-adverseeventsreporting a::after,#block-adverseeventsreportingblock2 a::after{content:" ";position:absolute;top:2em;right:1.5em;width:0;height:0;border-style:solid;border-width:0.6em 0.4em 0 0.4em;border-color:black transparent transparent transparent;}@media screen and (min-width:727px){#block-adverseeventsreporting a::after,#block-adverseeventsreportingblock2 a::after{top:0.5em;right:1.3em;}}@media screen and (min-width:991px){#block-adverseeventsreporting a::after,#block-adverseeventsreportingblock2 a::after{top:0.5em;right:-1.7em;}}
#block-patientaudiencemessage,#block-hcpaudiencemessage{background-color:#363739;}#block-patientaudiencemessage .text_content,#block-hcpaudiencemessage .text_content{max-width:1450px;margin:0 auto;padding:1em;}#block-patientaudiencemessage p,#block-hcpaudiencemessage p{font-size:14px;color:white;}#block-patientaudiencemessage a,#block-hcpaudiencemessage a{color:#F7CCE5;}