Submitted by Mr Humuun Admin on Thu, 04/21/2022 - 13:53

What is dengue?

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Dengue is a mosquito-borne viral disease that is prevalent in more than 100 countries worldwide.4-6

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The incidence of dengue has grown dramatically around the world in recent decades.4

Help protect travellers by vaccinating early

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Dose 1
0.5-mL
Administer at Month 0 (Day 1)1

Dose 2
0.5-mL
Administer at Month 3 (day 91)1

Exploratory data suggests that protection starts building from 3 weeks post first vaccination and persists up to 4.5 years following the second dose1

*Incidence of cases: 0.8% QdengaTM vs 3.3% placebo. Incidence of cases: 1.1% QdengaTM vs 3.2% placebo. 1

▼ This medicinal product is subject to additional monitoring.

GB & NI: Adverse Events should be reported. Reporting forms and information can be found at: www.mhra.gov.uk/yellowcard.

ROI: Adverse Events should be reported to the Pharmacovigilance Unit at the Health Products Regulatory Authority. Reporting forms and information can be found at: www.hpra.ie.

GB, NI and ROI: Adverse Events should also be reported to Takeda UK Ltd at: AE.GBR-IRL@takeda.com

 

References
  1. QdengaTM Summary of Product Characteristics
  2. Biswal S, et al. NEJM. 2019;381(21):2009-2019 and supplementary appendix.
  3. Biswal S, et al. Lancet. 2020;395:1423-1433 and supplementary appendix.
  4. World Health Organization. Dengue and severe dengue. 17 March 2023. Available at: https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue. Last accessed: November 2023.
  5. WHO. Vector-borne disease. 2021. Available at: https://www.who.int/news-room/fact-sheets/detail/vector-borne-diseases. Last accessed: November 2023.
  6. Jing Q and Wang M. Glo Health J. 2019;3(2):37-45.
  7. OutbreakObservatory. The global rise of dengue infections. Available at: https://www.outbreakobservatory.org/outbreakthursday-1/3/21/2019/the-global-rise-of-dengue-infections. Last accessed November 2023.

 

CI, confidence interval; VCD, virologically confirmed dengue; WHO, World Health Organization.

 

C-APROM/GB/DENV/0072 | Date of preparation: November 2023